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Hyaluronic acid has taken the skincare world by storm, and for good reason. This powerhouse ingredient is celebrated for its ability to hydrate, plump, and rejuvenate the skin, making it a must-have in any skincare routine.
If there is any skincare ingredient I recommend to anyone with any skin type or condition, it is hyaluronic acid. There is something weird about the pronunciation of hyaluronic acid – HYA-LU-RO-NIC acid. Hyaluronic acid can benefit any skin type, skin condition, age, or concern.
But what exactly is hyaluronic acid, and how can you incorporate it into your regimen effectively? This guide will break down everything you need to know about hyaluronic acid, from its benefits and side effects to how to use it for optimal results.
What Is Hyaluronic Acid?
Hyaluronic acid (HA) is a naturally occurring molecule found in our skin, eyes, and connective tissue. Itโs a type of glycosaminoglycan, a substance that helps retain moisture. In fact, hyaluronic acid can hold up to 1,000 times its weight in water, making it an incredible hydrator. Since it is present in our body when you apply hyaluronic acid topically, your skin recognizes it as one of its own ingredients. This makes hyaluronic acid well-accepted, well-tolerated and unlikely to irritate.
As we age, the natural levels of hyaluronic acid in our skin decrease, leading to dryness, fine lines, and a loss of elasticity. This is where topical hyaluronic acid steps in to replenish what time takes away.

Benefits of Hyaluronic Acid
1. Hydrates Your Skin
Hyaluronic acid is famous for its hydration properties. It draws moisture from the environment and locks it into your skin, keeping it supple and hydrated throughout the day. Whether you have dry, oily, or combination skin, HA works to maintain a balanced moisture level.
A 2014 study involved 33 females with an average age of 45, who applied topical hyaluronic acid as a lotion, serum, and cream. The result demonstrated increased hydration after 8 weeks of usage compared to untreated skin.
2. Plumping and Firming
By drawing moisture into the skin, hyaluronic acid helps to plump up fine lines and wrinkles, giving the skin a smoother, more youthful appearance. Itโs like a tall drink of water for your skin, filling in those lines from the inside out.
A 2014 study involving females after applying hyaluronic acid for 8 weeks reported a 40% decrease in wrinkle depth and a 55% increase in skin firmness.
3. Heals Wound
Hyaluronic acid modulates the tissue regeneration process involved in wound healing. A 2016 study suggests that applying hyaluronic acid helps heal wounds, relieves inflammation, and regulates tissue repair.
4. Relieves Joint Pain
Hyaluronic acid isn’t only available as a topical; you can also find it in pills and injectables. For joint pain relief, injectables or pills are preferred and are modestly effective in treating moderate knee osteoarthritis pain.
A 2017 study showed that combining hyaluronic acid with corticosteroid or non-steroidal anti-inflammatory medications can can boost the effectiveness of treatment for osteoarthritis pain.
5. Enhances Skin Barrier
A strong skin barrier is essential for protecting your skin against environmental aggressors like pollution and UV rays. Hyaluronic acid supports the skinโs barrier by keeping it hydrated and resilient, reducing the likelihood of irritation and redness.
In a 2011 study attempting to improve the skin barrier of those with dermatitis, hyaluronic acid foam was used to optimize the skin barrier. It was observed that the hyaluronic acid foam was more pleasant to use than the ceramide-containing cream.
How to Use Hyaluronic Acid in Your Skincare Routine
Incorporating hyaluronic acid into your skincare routine is simple and straightforward, but to maximize its benefits, there are a few tips you should keep in mind.
- Apply on Damp Skin
For hyaluronic acid to work its magic, it needs something to bind to. Applying it on damp skin allows the molecule to draw in moisture from the surface, locking it into the skin. After cleansing, leave your skin slightly damp before applying your hyaluronic acid serum or moisturizer. - Layering with Other Products
Hyaluronic acid is a versatile ingredient that can be layered with almost any other skincare product. However, for best results, it should be applied before heavier creams and oils. This ensures that it can penetrate the skin and deliver hydration where itโs needed most. - Use Morning and Night
For optimal hydration, you can use hyaluronic acid both in the morning and at night. In the morning, it helps prep your skin for the day, keeping it hydrated under makeup. At night, it aids in skin repair and rejuvenation. - Pair with a Moisturizer
To lock in the hydration provided by hyaluronic acid, always follow up with a moisturizer. This creates a seal over your skin, preventing the moisture from evaporating and ensuring that your skin stays plump and hydrated throughout the day. - Donโt Forget Sunscreen
While hyaluronic acid itself doesnโt increase sun sensitivity, itโs always important to apply sunscreen during the day. Sunscreen helps protect your skin from UV damage, which can exacerbate dryness and aging.
Side Effects of Hyaluronic Acid
Before you rush to buy hyaluronic acid serum or pills, there are some important things you need to know. Numerous studies show that the molecular size of hyaluronic acid is too large to penetrate and reach the dermis, the deepest layer of the skin.
Purging
Some users may experience a purging phase when they first start using hyaluronic acid, especially if theyโve added it to an exfoliating routine. This is a temporary process where your skin is adjusting to the new ingredient, and it should subside after a few weeks.
Allergic Reactions
Although rare, allergic reactions to hyaluronic acid can occur. Symptoms may include redness, itching, or a rash. If you experience any of these symptoms, discontinue use immediately and consult with a dermatologist.
Overuse Can Lead to Dryness
Ironically, overusing hyaluronic acid can sometimes lead to dryness. This occurs when HA draws moisture from the deeper layers of the skin rather than the environment, leaving the surface dehydrated. To avoid this, ensure youโre using HA on damp skin and not exceeding recommended usage.
Hyaluronic acid is also weather-dependent. Since it does not self-generate water, if you apply hyaluronic acid in a really humid environment, your skin will appear plump and bouncy. On the other hand, if you apply hyaluronic acid in an environment with less or no humidity, it will pull water from your skin, making your skin drier.
If you want to learn more about this, read up on the real truth about hyaluronic acid to understand how to use it properly.
Types Of Hyaluronic Acid
1. Hyaluronic Acid Injection Filler
The hyaluronic acid fillers are typically soft and gel-like. It is a very popular and safe procedure, hence it has received approval from the US. FDA. it bypasses all the skin layers, reaches the dermis, and boosts collagen production. This plumps and enhances the appearance of your skin. The results typically last for 6 to 12 months or longer.
2. Hyaluronic Acid Pills/Supplements
Since hyaluronic acid is already present in our bodies, the pills benefit the joints, eyes, and skin. Ingesting hyaluronic acid could enhance skin hydration since the molecular size of topical hyaluronic acids may be too large to penetrate the skin.
A 2021 study, involving 40 healthy males and females who took 120mg of hyaluronic acid pills per day for 12 weeks showed improvements in skin wrinkles, elasticity, and sagginess compared to those who did not take the pills.
There are still many gaps in research regarding hyaluronic acid pills, and the optimal dose remains uncertain. However, studies suggest that using hyaluronic acid supplements is safe, and there are indications of improvements in wrinkles and dry skin.
3. Hyaluronic Acid Multi Molecular Topicals
The cosmetic industry, aware of the issue with hyaluronic acid merely sitting on the skin, decided to break it down into simpler molecules that we have now. We have high molecular weight, middle molecular weight, and low molecular weight hyaluronic acid to ensure optimal penetration into all layers of the skin.
Best Hyaluronic Acid Serums
Niod Multi-Molecular Hyaluronic Acid Complex is a smart problem solver. It contains three different molecular weights of hyaluronic acid: one sits on top of your skin, one penetrates the middle layer, and one reaches the deep dermis layer, thereby plumping and radiating your skin.
Isdinceutics Hyaluronic acid concentrate contains middle and low-molecular weight hyaluronic acid, which easily absorbs into your skin to provide the hydration it needs.
It is worth noting that it contains fragrance, which could irritate those with sensitive skin. It is perfect for those with combination skin types.
Cerave Hyaluronic Acid Serum is perfect if you are looking for an affordable option that gets the job done. It also contains ceramide and vitamin B5 to lock in moisture. No matter what weather condition you are in, this is bound to work for you.
La Roche Posay Hyalu B5 is another great option for all skin types but it is mostly recommended for those with oily/acne-prone skin to plump fine lines and improve skin texture.
Paula’s Choice hyaluronic acid booster contains ceramide and vitamin B5 to improve skin texture and hydration. It is lightweight and absorbs well into the skin. It is great for all skin types.
Who Should Use Hyaluronic Acid?
The beauty of hyaluronic acid is that itโs suitable for everyone. Whether youโre in your 20s looking to maintain youthful skin or in your 50s seeking to restore hydration and plumpness, hyaluronic acid can fit seamlessly into your skincare routine. Itโs especially beneficial for those with dry or dehydrated skin, but even oily and acne-prone skin types can enjoy its lightweight, non-greasy hydration.
Conclusion
Hyaluronic acid is a skincare staple that delivers deep hydration, improved elasticity, and a smoother complexion. By incorporating it into your routine, you can enjoy plumper, more radiant skin at any age. Remember, consistency is keyโmake HA a regular part of your skincare regimen, and your skin will thank you for it!
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